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Fipronil is the primary ingredient in Frontline and Frontline Plus. There should be no side effects with this preventative and if your cat exhibits a reaction, get him to the vet immediately.

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11y ago

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See this site for possible side effects http://www.apnm.org/publications/resources/fleachemfin.pdf


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Fipronil is the medicinal ingredient in regular Frontline. For Frontline Plus, it's a combination of Fipronil and S-methoprene. For Frontline Plus, there is 9.8% of Fipronil and 11.8% of S-methoprene. The remaining 78.4% of ingredients in the Plus formula are inert. This information was obtained through various sources on the Internet. ,,,=^.,.^=,,, KatlovrNo1


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