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A fighting dog (e.g. Pit bull, bull terrier, staffie, Rottweiler) are only fighting dogs if they are trained to fight. If they haven't been trained, they would be as gentle as a pug.
Anyway, the physical difference is that, a fighting dog has more muscles and is much stronger. Most of the dogs listed above have been bred just for fighting, so are much more muscular than other dogs and have broader shoulders.
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