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suffix.
A prefix on an application for employment may refer to Mr. Miss, Ms. or Mrs. This is a title chosen by the applicant.
It could mean engineer and it is very similar to mr and mrs infront of names
Mr and Mrs
Mr and Mrs is correct or Mrs and Mr is correct
Mr. and Mrs. (ex. "Hello, Mr. and Mrs. Evans" instead of "Hello, Mrs. and Mr. Evans")
Mr. & Mrs. Smith
In the US it is normally Mr. and Mrs.
Dr. and Mrs. or Mr. and Dr.
I would address it to Mr and Mrs David Keys. For the salutation I would use Dear Mr and Mrs Keys.
Mr. used to be acceptable to address a household by just using the last name, e.g. "Mr. Jones". In modern times, it is typically to use "Mr. and Mrs. Jones" or "Mr. and Mrs. Timothy Jones".
Mr and Mrs its just more formal today in society.