It means to create a huge fuss over, or to make a big deal about.
Katy always makes such a big fuss when she doesn't get what she wants!
sex
My Sister/Brother Made A big Fuss Because They Had To Go TO bed.
Needlessly nervous or useless activity
It means that when you are a grown woman, you shouldn't fuss and cry over little things the way a small child would.
Fuss, Bustle
ado
umm pet it
Yes, she was, but did not make a big fuss of religion .
To give things to someone happily and kindly; to not fuss over it
ruckus