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Acupuncture is believed to stimulate the release of several chemicals in the body, including endorphins, which are natural pain relievers, and neurotransmitters like serotonin and dopamine, which can enhance mood and well-being. Additionally, acupuncture may promote the release of other neuropeptides and inflammatory mediators that help in pain modulation and healing processes. This biochemical response is thought to contribute to the therapeutic effects of acupuncture on various conditions.

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