Patients with plasmacytomas such as myeloma overproduce monoclonal immunoglobulins, also called M proteins. The Bence-Jones protein refers to the immunoglobulin light chain, a portion of these immunoglobulins.
Bence Jones proteins are small proteins (light chains of immunoblobulin) found in the urine. Testing for these proteins is done to diagnose and monitor multiple myeloma and other similar diseases.
.Multiple myeloma, a tumor of plasma cells, is the disease most often linked with Bence Jones proteins.Physicians use Bence Jones proteins testing to diagnose the disease as well as to check how well the disease is responding to treatment.
Normal results for a Bence Jones protein test should show no detectable levels of Bence Jones protein in the urine, indicating a healthy kidney function and no abnormal protein excretion. If Bence Jones protein is present in the urine, further investigation may be needed to determine the underlying cause.
Henry Bence Jones died in 1873.
Henry Bence Jones was born in 1813.
Bence Jones proteins are present in the urine of a patient suffering from multiple myeloma. Positive test means they are present in the urine and so the person probably has multiple myeloma, and if it is negative it means they are absent and so the person does not have the disease
The best specimen for a Bence Jones protein test is a 24-hour urine sample. This allows for the most accurate measurement of protein excretion over a full day, which is important for detecting and monitoring conditions such as multiple myeloma.
M. Bence-Jones has written: 'The Viceroys of India'
Mark Bence-Jones was born on 1930-05-29.
Mark Bence-Jones died on 2010-04-12.
Bence Jones proteins are abnormal proteins found in the urine, typically seen in conditions like multiple myeloma. A positive result for the lambda type means that the abnormal proteins detected belong to the lambda light chain subtype. This information is important for diagnosing and monitoring certain blood disorders.