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Bence Jones proteins are monoclonal immunoglobulin light chains found in the urine of patients, often associated with multiple myeloma. They are typically stable at room temperature for a short period but should ideally be stored at -20°C for long-term preservation. However, repeated freeze-thaw cycles can lead to denaturation and loss of function. Proper handling and storage are crucial for accurate diagnostic testing and analysis.
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What is a Bence-Jones protein?
Patients with plasmacytomas such as myeloma overproduce monoclonal immunoglobulins, also called M proteins. The Bence-Jones protein refers to the immunoglobulin light chain, a portion of these immunoglobulins.
What is a Bence Jones protein test?
Bence Jones proteins are small proteins (light chains of immunoblobulin) found in the urine. Testing for these proteins is done to diagnose and monitor multiple myeloma and other similar diseases.
What is the purpose of a Bence Jones protein test?
.Multiple myeloma, a tumor of plasma cells, is the disease most often linked with Bence Jones proteins.Physicians use Bence Jones proteins testing to diagnose the disease as well as to check how well the disease is responding to treatment.
What are normal results for a Bence Jones protein test?
Normal results for a Bence Jones protein test should show no detectable levels of Bence Jones protein in the urine, indicating a healthy kidney function and no abnormal protein excretion. If Bence Jones protein is present in the urine, further investigation may be needed to determine the underlying cause.
When did Henry Bence Jones die?
Henry Bence Jones died in 1873.
When was Henry Bence Jones born?
Henry Bence Jones was born in 1813.
Discuss the meaning of the positive and negative test for bence Jones?
Bence Jones proteins are present in the urine of a patient suffering from multiple myeloma. Positive test means they are present in the urine and so the person probably has multiple myeloma, and if it is negative it means they are absent and so the person does not have the disease
What is the best specimen for a Bence Jones protein test?
The best specimen for a Bence Jones protein test is a 24-hour urine sample. This allows for the most accurate measurement of protein excretion over a full day, which is important for detecting and monitoring conditions such as multiple myeloma.
When was Mark Bence-Jones born?
Mark Bence-Jones was born on 1930-05-29.
When did Mark Bence-Jones die?
Mark Bence-Jones died on 2010-04-12.
What has the author M Bence-Jones written?
M. Bence-Jones has written: 'The Viceroys of India'
Bence Jones protein positive lambda type?
Bence Jones proteins are abnormal proteins found in the urine, typically seen in conditions like multiple myeloma. A positive result for the lambda type means that the abnormal proteins detected belong to the lambda light chain subtype. This information is important for diagnosing and monitoring certain blood disorders.
