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A tubercule is an inflammatory nodule; most commonly this is in response to an intracellular bacteria (such as Mycobacterium) that the body is unable to get rid of. The inflammatory cells associated with the tubercule are macrophages (large cells that are trying to eat and break down the bacteria but are unable to) and fibroblasts (long spindly cells that are trying to make a shell of scar tissue to contain the bacteria).

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