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Why is levodopa and carbidopa given together?
Levodopa and carbidopa are given together to enhance the effectiveness of Parkinson's disease treatment. Levodopa is converted to dopamine in the brain, alleviating symptoms, but it can also be metabolized peripherally, leading to side effects. Carbidopa inhibits the enzyme that breaks down levodopa outside the brain, allowing more levodopa to reach the brain and reducing side effects like nausea and vomiting. This combination improves the overall efficacy of the therapy.
What are drug interactions with pyridoxine?
What are drug interactions with pyridoxine?
What is the chemical name for vitamin b6?
The chemical name for vitamin B6 is pyridoxine.
What is pyridoxine hydrochloride's chemical formula?
The chemical formula for pyridoxine hydrochloride is C8h11no.3hc1.
What does carbidopa do?
Levodopa itself is not well tolerated, which is why it is combined with carbidopa. Carbidopa decreases peripheral metabolism of levodopa, which allows for lower doses of levodopa and less-severe side effects.
How to avoid giving levodopa in high dose to Parkinson's patients?
Although levodopa can cross our BBB, but it will be decarboxylated to dopamine peripherally before reaching our CNS - only small amount of Levodopa will be left and available to pass our BBB.So, instead of giving levodopa in high dose (which can cause lots of side effects), we give levodopa with peripheral decarboxylase inhibitors (e.g. carbidopa, benserazide) which can inhibit decarboxylation of levodopa in GIT and peripheral tissues. (By combining levodopa and peripheral decarobxylase inhibitors, we will have less side effects too)
What is pyridoxine Hydrochloride?
Pyridoxine hydrochloride is the salt form of pyridoxine, which is a form of vitamin B6. Vitamin B6 is considered vital for human health.
Who discovered pyridoxine?
Pyridoxine was discovered by the Hungarian physician György Zemplén in 1934.
Why is Anti-TB drugs given with Vitamin B complex?
anti tb drugs.. such as isoniazid is given with vit b complex tablets because it combats the toxic side effects of the drug (INH). with regards to the interaction of Vit B to Isoniazid- it thus can increase pyridoxine requirements. pyridoxine is one of the compounds that can be called vitamin B6.summary:it is given with vitamin b complex to increase pyridoxine requirements (that assists in sodium and potassium balance in the body and promotes RBC production) and it combats the toxic side effects of the drug ISONIAZID/INH. anti tb drugs.. such as isoniazid is given with vit b complex tablets because it combats the toxic side effects of the drug (INH). with regards to the interaction of Vit B to Isoniazid- it thus can increase pyridoxine requirements. pyridoxine is one of the compounds that can be called vitamin B6.summary:it is given with vitamin b complex to increase pyridoxine requirements (that assists in sodium and potassium balance in the body and promotes RBC production) and it combats the toxic side effects of the drug ISONIAZID/INH. anti tb drugs.. such as isoniazid is given with vit b complex tablets because it combats the toxic side effects of the drug (INH). with regards to the interaction of Vit B to Isoniazid- it thus can increase pyridoxine requirements. pyridoxine is one of the compounds that can be called vitamin B6.summary:it is given with vitamin b complex to increase pyridoxine requirements (that assists in sodium and potassium balance in the body and promotes RBC production) and it combats the toxic side effects of the drug ISONIAZID/INH.from kaye kaye coraton
What is l dopa?
levodopa
What effect does pyridoxine have on pregnant women?
pyridoxine reduces the nausea for about a third of pregnant women who experience morning sickness . In addition, pyridoxine does not have any harmful effects on the fetus.
Is pyridoxine hydrochloride a chemical compound?
Yes, pyridoxine hydrochloride is a chemical compound. It is the hydrochloride salt form of pyridoxine, which is a form of vitamin B6. It is commonly used in dietary supplements and medications to treat vitamin B6 deficiency.
