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Coagulation is the process by which blood transforms from a liquid to a gel, forming a clot to stop bleeding. This involves a cascade of reactions among clotting factors, leading to the conversion of fibrinogen into fibrin, which forms a mesh that stabilizes the platelet plug. Fibrinolysis is the subsequent process that breaks down the clot once healing has occurred, primarily through the action of plasmin, which digests fibrin and restores normal blood flow. Together, these processes maintain hemostasis, ensuring that bleeding is controlled and tissue repair is facilitated.

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