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Not usually-- but keep in mind that the word "skeletal" is a word from the study of anatomy. It refers to the skeleton (our bones), and in that use, it has no connotation-- neither positive nor negative. But in slang and in casual language, "skeletal" refers to being too thin, as if you are starving yourself intentionally (a condition called "anorexia"). You would therefore say it has a negative connotation, because who wants to look like they are starving? Here's the usage: That actress thinks she looks stylish, but I am worried about her because to me, she looks skeletal.

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12y ago

What else can I help you with?