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The start of the QT interval is the first deviation from the isoelectric line following the p wave and the end is the last time the waveform crosses the isoelectric line before the T-wave begins. The waveform may well corss the isolelectric line several times before the end of the QRS interval. Normal measurement is less than or equal to .12

In simple terms, it is the start and end of the "spiky" high-frequency part of the waveform.

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