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Air exposure is not necessary for clot formation. Clotting occurs in a process called hemostasis, where platelets and clotting factors in the blood work together to form a plug at the site of a vessel injury. This process is triggered by the exposure of collagen and tissue factors when blood vessels are damaged, and it can happen in a closed system without direct contact with air. However, air exposure can affect the clot's stability and drying process after it has formed.

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2w ago

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