0
What else can I help you with?
Term for chemicals that cause fever?
Pyrogens are chemicals that cause fever by acting on the hypothalamus, increasing the body's temperature set point. Examples of pyrogens include bacterial toxins, cytokines, and prostaglandins.
Many fevers result from exposure to certain bacteria that release endogenous pyrogens that stimulate leukocytes to release chemicals known as endotoxins?
False
What substances cause a fever?
Fever is primarily caused by pyrogens, which are substances that induce an increase in body temperature. These can be either endogenous, produced by the body (like cytokines released during an immune response), or exogenous, originating from outside the body (such as bacterial toxins or viral components). Infections, inflammatory conditions, and certain medications can also trigger fever through these pyrogenic mechanisms.
The circulating substances that affect the hypothalamus and initiate fever are?
Cytokines such as interleukin-1, interleukin-6, and tumor necrosis factor-alpha are the main circulating substances that affect the hypothalamus and initiate fever by increasing the hypothalamic set point for body temperature. These cytokines are released in response to pathogens or inflammation in the body.
What poison is produced by high fever?
High fever can result in the production of endogenous toxins, such as cytokines, that can lead to systemic inflammation and tissue damage. This can contribute to symptoms such as body aches, malaise, and weakness during a fever.
What are some examples of pyrogens?
Some examples of pyrogens are bacterial endotoxins, such as lipopolysaccharides (LPS) found in the outer membrane of gram-negative bacteria, and certain viral and fungal components. These substances can induce fever by activating immune cells to release cytokines such as interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-α), which then act on the hypothalamus to raise body temperature.
What is the pathophysiology of a fever?
Fever is caused by infection .noninfectious causes are cancer,collagen vascular diseases,granulomatous diseases etc.Infectious causes releses pyrogens which produce pyrogenic cytokines, and non infectious causes directly stimulates release of pyrogenic cytokines, which go to vessels supplying hypothalamus(lamina ventricularis), where they produce PGE2 from endothelium of blood vessels,which makes thermostat of hypothalamus in a higher level, which causes fever.
High level of pyrogens in blood indicate?
circulating proteins called Pyrogens can reset this themostat and raise body temperature "fever"
Do pyrogens act by increasing the set point for body temperature in the thalamus?
No. Pyrogens act by increasing the temperature, but they do not change the set point in the thalamus.
What is the function of pyrogens?
inhibit bacterial growth
Why are aspirin and Ibuprofen anti pyrogens?
they reduce fever
Can pyrogens handle body temperatures that are above normal?
No
