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The oocyte or egg in the ovary is surrounded by cells that make up the follicle. Each month, one of the eggs and its corresponding follicle matures. There is a primoridal follicle, primary follicle, secondary follicle and finally a vesicular or Graafian follicle. The vesicular (Graafian) follicle is the most mature and the oocyte is suspended from a stalk into the flluid-filled compartment of the vesicular follicle. The egg or oocyte is released from the vesicular follicle at ovulation. The follicle remains in the ovary and develops into the corpus luteum, which secretes progesterone.

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