Answering "What is non-pyrogenic?" Pyrogenic: producing or produced by fever Substances which are non-pyrogenic in the medical sense of the word will not cause inflamatory or fever responses.
It means it will not cause a fever or heat.
A non-pyrogenic fluid path refers to a system that is free from substances that could cause a fever-like response when introduced into the body. This is crucial in medical devices and pharmaceutical products to prevent adverse reactions in patients. Materials used in non-pyrogenic fluid paths are carefully selected and manufactured to ensure they do not contain pyrogens.
A pyrogen is a substance that causes fever. Thus, to be pyrogenic is to cause fever.
Non-pyrogenic needles are used to prevent the introduction of pyrogens, which are substances that can cause fever and other adverse reactions in patients. These needles are essential in medical and pharmaceutical applications, particularly for injections and infusions, to ensure safety and minimize the risk of infection. Their use is critical in maintaining sterility and ensuring patient comfort during procedures.
fever
fever
An aerosil is a very fine, pyrogenic form of silica.
Body temperature increases for a while; fever
A pyrogenic activator is a substance that stimulates the immune system to produce pyrogens, which are fever-inducing compounds. These activators can trigger the release of pro-inflammatory cytokines, leading to an increase in body temperature as part of the immune response. Pyrogenic activators are often studied in the context of infections, immune disorders, and vaccine development. Their role is crucial in understanding how the body responds to pathogens and inflammation.
Fever is caused by infection .noninfectious causes are cancer,collagen vascular diseases,granulomatous diseases etc.Infectious causes releses pyrogens which produce pyrogenic cytokines, and non infectious causes directly stimulates release of pyrogenic cytokines, which go to vessels supplying hypothalamus(lamina ventricularis), where they produce PGE2 from endothelium of blood vessels,which makes thermostat of hypothalamus in a higher level, which causes fever.
sieve tube.