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q.d. is a Latin abbreviation for "quaque die," which translates in English to "every day" or "once daily." Daily dosages of medication can be given in a number of different modes.

p.o. is a Latin abbreviation for "per os," which translates in English to "by mouth" or "by way of the mouth."

A q.d. dose does not necessarily have to be given p.o.

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