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The prefix is polio and means brain or gray matter of the brain. Encephal- also means brain. And -malacia means softening. The combing vowel is the o between encephala- and -malacia.
According to medical dictionaries it means: 'Cerebrocortical necrosis in sheep and goats, also seen in cattle, deer, and antelope. Associated with thiamine deficiency, water deprivation-sodium ion toxicosis, lead poisoning, and particularly with high dietary sulfur levels leading to high hydrogen sulfide and acetic acid levels in the rumen, which adversely affect carbohydrate metabolism'.
In simpler words: soften of the brain which results in loss of motor function.

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