Thelicemia, also known as thalassemia, is a genetic blood disorder characterized by reduced production of hemoglobin, leading to anemia. It results from mutations in the genes responsible for hemoglobin synthesis, causing ineffective red blood cell production and their premature destruction. There are different types of thalassemia, including alpha and beta thalassemia, each varying in severity and treatment approaches. Management often involves blood transfusions, iron chelation therapy, and in some cases, bone marrow transplantation.