There are tens of thousands of answers to this question.
large, muave, opaque, clockwise, etc., etc., etc.
Dirty, bad, low, abject, squalid, filthy, wretched, sleazy...
Puzzling A+LS FTW
The root word for "wretched" is "wretch," which is a noun. "Wretch" refers to a miserable or unfortunate person, and the adjective "wretched" describes a state of deep misery or distress. The term conveys a sense of suffering or extreme discomfort.
The term "word" has the synonyms article, designation, phrasing, text, or term.
Credibility
upset, worried, troubled, distracted, tormented, distraught, agitated, wretched
Wretched, miserable, hopeless, pathetic, pitiful are all synonyms for abject
Indifference
A wretched witch kidnapped me when I was 5 years old.
some animals are kept in the most wretched conditions.
"Animal biology" is the closest term.
An informal synonym for the term optimal is the word ace. Ideal is also a good synonym, as well as matchless. There are a lot of other synonyms that can be found in a thesaurus or online.