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D-Dimer is a product of fibrin degradation, which is a protein fragment present after a blood clot is degraded through fibrinolysis (a test used to analyze blood clots). A fibrin is a non-globular protein that results from the coagulation (clotting process) of blood.

On an atomic level, the fibrin protein has two D fragments, cross-linked between an E fragment. In biochemical terms, it is expressed as D-E-D, which is where the D in D-dimer comes from.

The test for D-dimer was not discovered until the 1970's, and practical applications were not found until the 1990's. It is currently used to test for and identify numerous clotting related blood disorders.

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12y ago

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