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Frances Lowell did not directly invent the cotton gin; that credit goes to Eli Whitney in 1793. However, Lowell was instrumental in the broader textile industry, particularly through the establishment of the Lowell System, which integrated the cotton manufacturing process and improved efficiency in textile production. His contributions helped to increase the demand for cotton, thereby amplifying the impact of Whitney's cotton gin by making cotton a central commodity in American manufacturing. Lowell's innovations ultimately shaped the economic landscape of the textile industry in the early 19th century.

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