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Her half brother died of AIDS and her half sister died of drugs.

Oprah has 3 half-siblings by her mother, two of whom have died and one who is alive and well..

One half-brother, Jeffrey, died of AIDS in 1988.

Patricia, her half sister, died of a drug addiction in 2003.

Her other half sister, also named Patricia was revealed on January 24, 2011 and is alive and well.

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