Yes , Izzy and George both will die and replaced by new character residents .
Izzie doesn't die, she gets cancer, but she never dies.
Izzy Stevens
Izzy Johnston was born on February 22 1984 which means that she is 27.
yes she will! The actess wanted to get out of the series!
Sharon Lawrence plays Izzy's mother "Robbie'
Izzy Goldstein died in 1993.
Izzy Jannazzo died in 1995.
Izzy Orloff died in 1983.
Izzy Gomez - restaurateur - died in 1944.
Izzy León died on 2002-07-25.
Jay Snaith
Izzy Leon died July 25, 2002, in Miami, FL, USA.
Harry might Marry Izzy but He is not going to be marry her Just yet as they are both still so young.
Izzy Goldstein died September 24, 1993, in Delray Beach, FL, USA.
Izzy Sparber died on August 29, 1958, in New York City, New York, USA.
Izzy Berne died on January 4, 1983, in Burbank, California, USA of heart attack.
Harry Judd and Izzy Johnston are still together as far as I know and Have been for a while now