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French contact with First Nations peoples had both positive and negative effects. On the positive side, it facilitated trade, cultural exchange, and alliances, particularly in the fur trade, which benefited both parties economically. However, harmful effects included the spread of diseases to which Indigenous populations had no immunity, leading to significant population declines, and the disruption of traditional ways of life due to European colonization and land exploitation. These interactions often resulted in long-term social and cultural changes for First Nations communities.

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