Nobody. Lois is alive.
While that is an interesting theory, there is simply no evidence to suggest it is true... so No.
None of them technically. He was "killed" in Lois Kills Stewie but it turned out it was a computer simulation so he didn't actually die.
Lois Lane was created in 1938.
Lois Pennycandy is Krusty The Clown's executive assistant.
Technically no one killed him since the death was erased from the timeline by Stewie, however, since the "Who" wasn't the focus of the episode they never had anyone killing him, it was juts a randomly driven car.
Lois Griffin is alive, but Stewie killed her in a simulation in the 100th episode
Lois McArthur was killed by her husband, Dr. Joe McArthur, in a crime of passion. He confessed to the murder during a police interrogation.
buck was
Her father killed her sister and Lois could not handle the pain.
Zero.
Louis riel was haug because he killed thomas Scott who was a bad person and killed lot's of people.
Lois Lowry's daughter was killed in a tragic accident in 1992. This personal tragedy deeply impacted Lowry and influenced her writing.
She was hit by a car and killed.
In "Number the Stars" by Lois Lowry, Ellen Rosen, Annemarie's best friend, was not killed. Ellen was Jewish and the Rosens arranged for her to be smuggled to safety in Sweden just before the Nazis planned to deport all Jews.
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While that is an interesting theory, there is simply no evidence to suggest it is true... so No.
The possessive form for the proper noun Lois is Lois's.Example: I will be at my friend Lois's house.