Spider-Man doesn't have a 'main villain' and, like most superheroes, fought a variety of characters. His main villains would likely be Dr. Octopus, Green Goblin, and Venom. (The majority of his villains follow an animal theme: Scorpion, Dr. Octopus, Rhino, Vulture, Venom/Carnage (spider), etc.)
Green Goblin/Norman Osborn
Yes, in the first Spiderman, Peter Parker has Thanksgiving (?) dinner with the Green Goblin, Harry's dad, and Harry, who turns out to be a sort of second Green Goblin in the third Spiderman, but he doesn't know it at the time.
Well In The First Season Of Scooby-Doo. Scooby-Doo Where Are You The First Villain Is The Black Night. And The person "Behind" The Black Night Was The Currator Of The Musuem. Mr. Wickles. =D
Norman Stansfield was the villain in The Professional
Spiderman 1, 2, and 3.
No one is the villain since a sequel to The Simpsons Movie doesn't and will not exist for some time.
It is in the movie Spiderman.
Which villain spiderman fears the most
Venom
No you can only be spiderman and black spiderman.
spiderman first got the black suit at the end of the secret wars number 8
SPIDERMAN
megatron
I know he played a villain in "Lucky Number Slevin".
shikari
Yes, in the first Spiderman, Peter Parker has Thanksgiving (?) dinner with the Green Goblin, Harry's dad, and Harry, who turns out to be a sort of second Green Goblin in the third Spiderman, but he doesn't know it at the time.
Spiderman in 2002.
the green goblin