meg and stewie (Family Guy may deny this) were based off of Meg and Charels Wallace from A Wrinkle in Time. The daughter thinks she's ugly and etc., and the son is a genius. Look it up. (not the movie- the movie was bad)
-- It should be noted that the above answer is opinion based only. There is no solid evidence, i.e. interviews with the Seth MacFarlane or cast, that proves this. After all, in Stewie's case, Seth has stated Stewie was based on British actor Rex Harrison.
Ron
The main characters in Family Guy are Peter, his wife Lois, children Chris, Meg, and Stewie, and dog Brian. Peter, Stewie, Brian, and Quagmire are all voiced by creator Seth MacFarlane.
He sang Rocketman
She Is The Daughter Of Lois & Peter Griffin & Sister Of Chris & Stewie Griffin.
You may be referring to When You Wish Upon a Weinstein
Stewie, Meg, Chris, Susie
Meg is 18Chris is 13 (unofficially 14)Stewie is 1
Eat broccoli, talk/spend time with meg
Meg
Lois Griffin from the TV show "Family Guy" has three children: Meg, Chris, and Stewie. Meg is the eldest and the only daughter, while Chris and Stewie are her two sons.
Season 4|Episode 13 Jungle Love
Bertram was Peter's son & Stewie, Chris & Meg's half-brother... however only Stewie (& Brian) knew he existed and neither Stewie nor Bertram knew they were actually related.
Season 8 | Episode 13: "Go Stewie Go"
Peter, Stewie, Louis, Brian, Meg, Chris, and Quagmire. Peter, Stewie, Louis, Brian, Meg, Chris, and Quagmire.
There's no such episode where Lois does it in front of both Meg & Peter.She is however, caught kissing Meg's boyfriend in Go Stewie Go
Ron
The main characters in Family Guy are Peter, his wife Lois, children Chris, Meg, and Stewie, and dog Brian. Peter, Stewie, Brian, and Quagmire are all voiced by creator Seth MacFarlane.