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Definitely Darth Vader. Mewtwo is a Poke'mon which means he is not sentient, so he will behave like an animal only with crazy powers. Darth Vader on the other hand is a human so he can think things threw and act on reasoning not just instinct. Besides the intelligence factor Darth Vader is also a ruthless sith who is extremely strong in the force. So Vader would absolutely defeat Mewtwo and any other Poke'mon.

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14y ago

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