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Etoricoxib tab

Trade name Arcoxia

Drug class Cycloxygenase-2 (COX-2) inhibitor

Presentation 60mg: Dark green apple-shape biconvex film coated tablets debossed ARCOXIA

60 on one side and 200 on the other side.

90mg: White apple-shape biconvex film coated tablets debossed ARCOXIA 90

on one side and 202 on the other side.

120mg: Pale green apple-shape biconvex film coated tablets debossed

ARCOXIA 120 on one side and 204 on the other side.

Cost 60mg: RM3.20/tab; 90mg: RM3.20/tab; 120mg: RM5.20/tab.

Prescriber Orthopaedics, Pain management team

Indication Acute and chronic treatment of osteoarthritis (OA) & rheumatoid Arthritis (RA).

Treatment of acute gouty arthritis, acute pain, including that related to primary

dysmenorrhea and minor dental procedures.

Dose Osteoarthritis: 60mg once daily.

Rheumatoid arthritis: 90mg once daily.

Acute gouty arthritis, acute pain and primary dysmenorrhea: 120mg once

daily. The 120mg dose used only for the acute symptomatic period, limited to a

max of 8 days treatment.

Hepatic Insufficiency: Mild (Child-Pugh score 5-6): Max: 60mg once daily.

Moderate (Child-Pugh score 7-9): Max: 60mg every other day should not be

exceeded. Moderate (Child-Pugh score >9): no clinical or pharmacokinetic data.

Renal Insufficiency: not recommended in advanced renal disease (creatinine

clearance <30ml/min). No dosage adjustment is necessary in patients with lesser

degrees of renal insufficiency (creatinine clearance ≥ 30ml/min)

Location Kedai PharmUMMC

Administration Taken with or without food.

Stability / expiry Store at 30°C (86°F). Protect from moisture and light.

Special precautions • Contraindicated in patients with hypersensitivity to any component of this

product, congestive Heart Failure (NYHA II-IV), established ischaemic heart

disease, peripheral arterial disease and/or cerebrovascular disease (including

patients who have recently undergone coronary bypass graft surgery or

angioplasty), hypertension whose blood pressure has not been adequately

controlled and in those who are pregnant.

• Risk of thrombotic events may increase with dose and duration of exposure,

the shortest duration possible with the lowest effective dose should be used.

• Concurrent use with aspirin may increase the risk of GI adverse effects.

• Gaution in patients who have previously experienced acute asthmatic

attacks, urticaria, or rhinitis, which were precipitated by salicylates or nonselective

cyclooxygenase inhibitors.

Special notes All to pay full cost.

Patient Information May cause hypotension, body pain, dizziness, constipation, agitation, insomnia,

GI effects, pruritus and increase sweating.

Prepared/checked by Yeap Li Ling / PDS / PL

Date compiled/edition 5 June 2009, 1st edition

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