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The answer to such a question depends on your ultimate destination in The Florida Keys. For instance, depending on the exact route, the distance between Tampa and, say, Key Largo (the northernmost island in the Florida Keys) can range from 295 to 325 miles. Meanwhile, the distance between Tampa and Key West (which is located at the southern end of the Florida Keys) can range from 400 to 425 miles.

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10y ago
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14y ago

The driving distance in miles between Orlando, Florida, and the Florida Keys is 379 miles.

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7y ago

The Keys are 120 miles long. Orlando to Key West is 393 miles.

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7y ago

The Keys are 120 miles long. Orlando to Key West is 393 miles.

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7y ago

The Keys are 120 miles long. Tampa to Key West is 425 miles.

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Q: What is the driving distance between Tampa and the Florida keys?
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