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The answer to such a question depends on your ultimate destination in The Florida Keys. For instance, depending on the exact route, the distance between Tampa and, say, Key Largo (the northernmost island in the Florida Keys) can range from 295 to 325 miles. Meanwhile, the distance between Tampa and Key West (which is located at the southern end of the Florida Keys) can range from 400 to 425 miles.

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12y ago

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