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Normally adrenaline act through the alpha and beta receptors . alpha receptors are vasoconstructive and beta are vaso dilatives . alpha are not as senstive as beta to the level of adrenaline. when adrenaline is given there is continuous fall in in bp.

Explanation..........

Adr is given rapidly by i.v route, it increases BP proportional to dose. It causes increase in systolic pressure is greater than diastolic pressure, so pulse pressure (difference between systolic & diastolic pressure) is also increases. This occurs due to α receptor response predominant and vasoconstriction occurs also at skeletal muscle. (Increase in BP by 3 mechanism: myocardial stimulation, increase HR and vasoconstriction in most of the body.)

When Adr is given by slow i.v infusion or s.c route, it causes increase in systolic pressure due to cardiac contractile force and increase in CO but decrease in diastolicpressure due to β2 receptors of skeletal muscle causing vasodilation. So Mean BP is decreased.

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