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There has not been a case of smallpox in the United States since 1949, except for a limited number of laboratory acquired cases. This disease is no longer a threat. In 1980, the World Health Organization (WHO) announced that smallpox was wiped out .

In case the disease is used in a biological attack, public health officials have a rapid response plan and will vaccinate those at risk. Vaccinations are not recommended at present, but the vaccine is in storage in case it is needed.

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Q: What state in the US has had the most outbrakes of smallpox?
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What famous people have died from smallpox?

Some of the most famous people that you may be aware of who had smallpox were US presidents George Washington, Andrew Jackson, and Abraham Lincoln. Soviet leader Joseph Stalin also had smallpox.


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After the eradication of smallpox, the last samples of smallpox were kept for academic research in Centers for Disease Control and Prevention in the US and State Research Centre of Virology and Biotechnology in Russia. Both these institutions are under heavy guard to avoid the possibility of the theft of the samples for biological warfare.


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