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Unrestrained of cells in or on the body can be a tumor. This can be non-cancerous or cancerous. Since you are looking at a "disease caused by unrestrained growth of abnormal cells", I would suggest cancer.

Non-cancerous growth can cause problems that can be called diseases. A large growth of non-cancerous cells can cause problems of the pancreas called pancreatitis.

Cancerous growths of the pancreas can cause blockage of the bile ducts causing jaundice.

There are many other example of these.

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