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After puberty, the epiphyseal plate, also known as the growth plate, undergoes a process called endochondral ossification, where it gradually calcifies. This leads to the fusion of the epiphysis with the diaphysis of the bone, marking the end of longitudinal growth in height. Once the epiphyseal plate is completely replaced by bone, further growth in length ceases, and the individual reaches their adult height. This process is influenced by hormones, particularly sex hormones like estrogen and testosterone.

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