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The large intestine is not transplanted because it is not necessary to sustain life; it is considered much safer to remove a malfunctioning large intestine (i.e perform a colectomy) than it is to then transplant a new one in it's place.

There are no published cases of large-intestine transplants or full intestine transplants being performed. (However small intestine transplants are now routinely performed). That's not to say that "it is not medically possible to transplant a large intestine", it just means that any 'benefits' are outweighed by the additional risks involved in transplantation (including but not limited to rejection, infection and side-effects of immuno-suppressives).

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