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Yes. Most cases of achondroplasia are associated with a dominant mutant form of the FGFR3 gene. Thus, if someone with achondroplasia has children with a person without achondroplasia, 50% of the offspring would be predicted to inherit the disorder. If two people with achondroplasia were to have children, 50% would inherit acondroplasia (i.e. would be heterozygous for the mutant FGFR3 allele), 25% would be normal, and 25% would inherit two copies of the mutant FGFR3 allele, a condition which is almost certainly lethal.

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Related Questions

Who is affected achondroplasia?

The offspring of the parents are affected


Is achondroplasia nondisjunction?

No, achondroplasia is not caused by nondisjunction. Achondroplasia is a genetic disorder caused by a spontaneous mutation in a gene involved in bone growth. Nondisjunction is a genetic event that occurs during cell division and can lead to abnormal chromosome numbers in offspring.


How is achondroplasia passed on?

When a mother gives birth (naturally) to a child who has it, the mother may transmit it during birth


Can a mutation be passed on to offspring?

Not usually. Only In certain circumstances, can a mutation be passed on to offspring; such as Downs-syndrome.


What can predict whether a mutation in a human skin cell can be passed to its offspring?

A mutation in a human skin cannot be passed on to an offspring, since it is only a somatic mutation which is acquired. The mutation that can be passed on to an offspring is called a germline mutation, which happens in the egg and sperm.


The triat that appears in the offspring is called?

the characteristics which are passed on by to a offspring by its parents


The mutations that breeders induce in organisms are passed on to the organisms?

offspring


What are genetic traits?

Genetic traits are variations of features passed on to offspring from there parents.


Can a mutation in the retina be passed on to the offspring?

No.


What will determine the genotype of an organism?

The alleles that are passed from parents to offspring


Do mutations occur in a body cell can be passed on to an offspring?

Mutations in body cells are not typically passed on to offspring because they occur in somatic cells, which are not involved in reproduction. However, mutations in germ cells (sperm or egg) can be passed on to offspring.


What is one characteristic passed from parent to offspring through genes?

The sex of the offspring.