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Not as such... It is a noble gas so does not react with your body if you breath it in. However it is deadly in extremely high quantities (as with all gasses apart from oxygen). ie. if you are in a room with solely neon gas then it would kill you by asphyxiation due to lack of oxygen but apart from that it is not toxic.

EDIT: Oxygen toxicity can occur as well. Extremely elevated Oxygen levels in the air you are breathing and elevated Oxygen levels with elevated pressure levels (such as found under water) can result in hyperoxia. This is a condition that can affect the eyes, brain, and heart. The results include increased oxidation of cellular membranes (destroys body cells), collapse of alveoli within the lungs (lungs fail), retinal detachment (eyes develop problems) and seizures(self explanatory). It should not be assumed that Oxygen is non-toxic merely because you require it for life.

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