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A nucleus is the center of an atom, with the protons and neutrons. A chemical reaction is a reaction between one or more elements that changes it (or them) into a new substance, like frying an egg, or mixing baking soda and vinegar with baking soda.

A NUCLEAR reaction (if that is what you were looking for) is a reaction between different atoms that causes them to fuse or break apart, becoming a new element, like fusing lithium and hydrogen to make helium. Nuclear reactions usually make ALOT of energy. Just look at the Sun.

(WARNING: I don't actually mean for you to actually look at the Sun, since you can blind yourself. I just mean for you to use the Sun as an example.)
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