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The sodium-potassium pump is an active pump working against an electrochemical gradient, and cuts ATP to ADP with every transfer of sodium and potassium across acell membrane.

Most motor proteins are also ATPases, requiring the lysing of ATP with each "movement" of the motor protein in order to function. This is actually the cause ofrigor mortis; although ATP is not needed to cause the muscle's motor proteins to constrict, it is required to allow them to slide past one another into the resting state once more. As death halts respiration, and thus ATP creation, the muscles can become rigid, but cannot relax again (not until other decay processes simply cause these proteins to decay altogether).

The hydrogen-potassium pump that regulates acidity of the stomach contents is also an ATPase.

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