Aldol condensation is the reaction of two aldehydes in the presence of a basic catalyst. The aldol condensation leads to an aldol product, in which an hydroxyl group is attached to the beta carbon of an aldehyde.
Claisen condensation is similar to aldol condensation, but is involves two esters instead of two aldehydes. The product of a Claisen condensation is a beta-keto-ester, a compound characterized by an ester with its alpha carbon being a ketone.
Of course,The Claisen Condensation is typically the reaction between two esters, in the presence of base, leading to formation of an ester enolate that reacts with an uncharged ester, thereby displacing it's "alcohol part" as the leaving group. The sequence leads to the formation of beta ketoesters. The intramolecular (cyclic) version of the Claisen Condensation is known as the Dieckmann Condensation, and is illustrated through the article, "Dieckmann Condensation Missing Piece."
Two of the most important from an academic standpoint are the Aldol addition which involves combining aldehyde, ketones or N,N-disubstituted esters to form more complex molecues. In the case of a biological system single collagen proteins are linked to form cross- linked collagen via an aldol addition of 2 aldehyde molecules, as well as the claisen condensation which is best known for the reaction between 2 thioesters acetyl thioester and malonyl thioester to form part of a fatty acid used in protein synthesis.
Of course,The Claisen Condensation is typically the reaction between two esters, in the presence of base, leading to formation of an ester enolate that reacts with an uncharged ester, thereby displacing it's "alcohol part" as the leaving group. The sequence leads to the formation of beta ketoesters. The intramolecular (cyclic) version of the Claisen Condensation is known as the Dieckmann Condensation, and is illustrated through the article, "Dieckmann Condensation Missing Piece."
Aldol condensation is the reaction of two aldehydes in the presence of a basic catalyst. The aldol condensation leads to an aldol product, in which an hydroxyl group is attached to the beta carbon of an aldehyde. Claisen condensation is similar to aldol condensation, but is involves two esters instead of two aldehydes. The product of a Claisen condensation is a beta-keto-ester, a compound characterized by an ester with its alpha carbon being a ketone.
SHYUKGHKY
1881
The key difference between the aldol and Claisen reactions in organic chemistry is the type of starting materials involved. In the aldol reaction, a carbonyl compound reacts with another carbonyl compound or an enolate ion to form a beta-hydroxy carbonyl compound. In the Claisen reaction, an ester reacts with a strong base to form a beta-keto ester. Both reactions involve the formation of new carbon-carbon bonds, but the aldol reaction involves carbonyl compounds while the Claisen reaction involves esters.
The Claisen-Schmidt reaction is a condensation reaction between an aldehyde or a ketone and an aromatic aldehyde that proceeds through the formation of an enolate ion from one of the carbonyl compounds. This enolate ion then attacks the carbonyl group of the aromatic aldehyde, leading to the formation of a β-hydroxy-α,β-unsaturated aldehyde or ketone. The reaction is typically base-catalyzed and proceeds via nucleophilic addition-elimination mechanism.
Not really because aldol condensation of 2 CH3CHO would be a major competing process.
is a condensation reaction in which an amines are allowed to react with acids to form amides.first amine react with acid and form an amide.again formed amide reacts with an acid to form an second amide called benzimidazole[which has similar structure of benzene] it has basic nucleus of imidazole
Rainer Ludwig Claisen died on 1930-01-05.
Rainer Ludwig Claisen was born on 1851-01-14.
Two of the most important from an academic standpoint are the Aldol addition which involves combining aldehyde, ketones or N,N-disubstituted esters to form more complex molecues. In the case of a biological system single collagen proteins are linked to form cross- linked collagen via an aldol addition of 2 aldehyde molecules, as well as the claisen condensation which is best known for the reaction between 2 thioesters acetyl thioester and malonyl thioester to form part of a fatty acid used in protein synthesis.
1,4-diphenyl-1,3-butadiene can be synthesized by reacting benzaldehyde with a halogenated compound like 1,4-dibromobutane. The first step involves a Knoevenagel condensation reaction between benzaldehyde and malononitrile to form a β-diketone intermediate. This intermediate then undergoes a base-catalyzed Claisen condensation with 1,4-dibromobutane to yield 1,4-diphenyl-1,3-butadiene.