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Cystic Fibrosis has an autosomal recessive pattern of inheritance, therefore, neither male nor female is more likely to inherit the disease.

There are four different scenarios that can occur to "pass on" the disease.

First, both parents have CF, and in this scenario all offspring would have CF as well.

Second, One parent has CF and the other doesn't. This scenario has two subgroups. The parent that does not have CF could either be a carrier or have no CF gene. If the non-CF parent is a carrier then 3 out of 4 children would inherit CF. If the non-CF parent is not a carrier then 2 of 4 children would inherit it.

Third, both parents are carriers, and in this scenario 2 of 4 offspring would inherit CF.

Fourth, one parent is a carrier and the other is not. This would yield 1 out of 4 offspring inheriting CF.

The genes for CF are located on non-sex chromosomes (autosomes) and therefore there is no correlation to Cystic Fibrosis and sex.

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13y ago

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