0
mutation in a single DNA base may have no effect on the phenotype or may have a great effect. the best example on this is sickle cell anaemia.
haemoglobin is formed of 2 alpha chains of protein and 2 beta chains, this is the beginning of the a.a sequence of beta chains: val-his-leu-thr-pro-glu-glu-lys
in some people, the mutation causes the substitution of a single thymine base with adenine. this causes one of the glutamine molecules with valine so the chain is this:
val-his-leu-thr-pro-val-glu-lys .
this very slight change causes the blood to form fibrous structures when it's not combined with oxygen. this causes many rbcs to be useless at transporting oxygen and the fibers may get stuck in capillaries which will prevent unaffected cells from getting through.
What else can I help you with?
WhIch best describes the initial change cause by a DNA mutation?
A DNA mutation can lead to changes in the sequence of nucleotides in the DNA, which can alter the instructions for building proteins. These changes can result in the production of a faulty protein or a non-functional protein, which can affect the normal functioning of cells and potentially lead to disease or other conditions.
What is a mutation disease?
A mutation is a permanent change in the DNA sequence of a gene. It may be a minor or a major change; and may be harmful or beneficial.RegardsTime is imaginary
How can mutation in DNA disrupt proper functioning?
A mutation in a gene can change the amino acid sequence of the protein the gene makes. These alterations in the proteins' primary structure may affect the secondary, tertiary, and quaternary structure, all which have to be exact for proper functioning. The mutation in a gene can also put a STOP message in the sequence so the protein is terminated prematurely, leading to a truncated polypeptide. Some polypeptides simply won't work, and when critical proteins are not functioning, the cell can cease to run metabolic reactions or undergo mitosis. Other polypeptides will become deleterious and directly harm the cell.
What is dominant negative mutation?
A negative mutation is one which is harmful to the organism. The result of a negative mutation is a non-sense protein. Examples of negative mutations include:a frame shift mutation - codons are read wrongan insertion mutation - insertion of a sequence of extra nucleotidesa deletion mutation - deletion of a chain of nucleotidesa non-sense mutation - results in the creation of a non-sense proteina transition mutation - exchange of purines to pyrimidines thus changing the nucleotide sequence and resulting in a mutation.
A mutation is harmful to an organism if?
Mutations are harmful if they decrease the function of some part of the body. Unfortunately, this is the case far more often than them making an improvement.
Sometimes genes are damaged or are copied incorrectly resulting in faulty?
When genes are damaged or copied incorrectly, it can lead to mutations. Mutations can affect how proteins are made in the body, which can disrupt normal cellular functions and potentially lead to diseases or disorders. Genes can be damaged by environmental factors like UV radiation or through errors during cell division.
WhIch best describes the initial change cause by a DNA mutation?
A DNA mutation can lead to changes in the sequence of nucleotides in the DNA, which can alter the instructions for building proteins. These changes can result in the production of a faulty protein or a non-functional protein, which can affect the normal functioning of cells and potentially lead to disease or other conditions.
Genes can mutate through replication error or through contact with a mutagen What can be a result of a mutation?
A mutation can lead to changes in a gene's sequence, potentially altering its function. This can result in the production of abnormal proteins, which could affect normal biological processes. In some cases, mutations can also cause genetic diseases or increase an individual's risk of developing cancer.
When when a mutation results in no significant change in the production of a of a functional protein?
When a mutation does not change the result of a normal production of a protein is called harmless. This is because it does no harm to the individual.
How does heat shock affect bacteria?
Heat shock can affect bacteria by causing their proteins to denature, or unfold, which can disrupt their normal functions and potentially lead to cell death. This stress response can also trigger the production of heat shock proteins, which help the bacteria survive and adapt to the stressful conditions.
Does fragile x syndrom have a mutation?
Yes, fragile X syndrome is caused by a mutation in the FMR1 gene on the X chromosome. This mutation leads to a lack of production of a protein called FMRP, which is essential for normal brain development.
What will mutation do if it does not occur in sex cells?
Mutations which do not occur in sex cells are not passed on to the next generation. The mutation will only affect the individual. They could therefore have normal offspring.
What do mutations in genes cause?
Mutations in genes can cause changes in the structure or function of the corresponding proteins, leading to various outcomes such as genetic disorders, cancer, or altered traits. Mutations can disrupt normal cellular processes, affect gene regulation, or result in the production of abnormal proteins.
What is a mutation disease?
A mutation is a permanent change in the DNA sequence of a gene. It may be a minor or a major change; and may be harmful or beneficial.RegardsTime is imaginary
A new mutation in mice cause the coast to be twice as normal In what environment would this mutation be helpful why?
New mutation in mice causes the coast to be normal in today's world. This is a well ask question.
Should you have Cancer?
No, Cancer is a mutation. It is not normal.
How does a somatic mutation in a gene alter the function of a cell?
A somatic mutation in a gene can alter the function of a cell by changing the instructions encoded in the gene, leading to abnormal protein production or function. This can disrupt normal cellular processes and potentially contribute to diseases like cancer.
