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Patients with sporadic prion diseases may have a susceptibility polymorphism in their PRNP gene, and may have spontaneous mutations forming prion proteins.

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14y ago

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How common is chronic Creutzfeldt-Jakob disease?

Sporadic CJD, with no recognizable pattern of transmission, has an incidence of about one case per million people per year worldwide, making up 85% of total CJD cases, and 80% of all prion disease cases.


What is Secondary structure of prion proteins in prion disease like Creutz feldt-Jakob disease (CJD)?

Secondary structure of prion proteins in prion disease like Creutz feldt-Jakob disease (CJD) is


How serious is prion disease?

All prion diseases are inevitably fatal; there are no known cures.


What is a well known prion disease?

There are multiple prion diseases, including bovine spongiform encephalopathy (BSE), or "mad cow disease."


What is familial CJD?

Familial Creutzfeldt-Jakob disease (CJD) is a rare genetic form of prion disease that causes rapid mental and physical deterioration. It is characterized by progressive dementia, muscle stiffness, and coordination problems. Familial CJD is caused by a mutation in the PRNP gene, which leads to the misfolding of prion proteins in the brain.


Which of these causes mad cow disease?

prion


Nonliving particle that causes disease?

A prion.


What is the pathogen that causes Mad Cow Disease?

A prion, or misfolded protein caused by genetic mutation.


Is chronic wasting disease a virus?

NO. It is caused by a PRION, not a virus.


Can prions affect a prion?

Yes, prions can interact with and convert other normal proteins into misfolded prion proteins, propagating the disease process. This conversion leads to the accumulation of abnormal prions in the brain, causing neurodegenerative diseases such as Creutzfeldt-Jakob disease.


What is the scientific name of the pathogen that causes mad cow disease?

A prion.


Mad cow disease is the result of infection of cattle with what agent?

A prion.