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Sickle-cell anemia is a genetic disorder, so you can only get it by being born with it. Sickle-cell anemia is much more prevalent in people of African descent because of its evolutionary advantage in regions where malaria is common. While having sickle-cell anemia is clearly detrimental to survival, having only one allele (instead of both) of the gene coding for sickle-cell anemia results in higher tolerance to the effects of malaria once infected with it. The greater number of people having only one allele leads to greater chance of their offspring having both, resulting in sickle-cell disease.

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14y ago

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