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The chemical warfare agent 3-quinuclidinyl benzilate (QNB, BZ) is an anticholinergic agent that affects both the peripheral and central nervous systems (CNS). It is one of the most potent anticholinergic psychomimetics known, with only small doses necessary to produce incapacitation. It is classified as a hallucinogenic chemical warfare agent. QNB usually is disseminated as an aerosol, and the primary route of absorption is through the respiratory system. Absorption also can occur through the skin or gastrointestinal tract. It is odorless. QNB's pharmacologic activity is similar to other anticholinergic drugs (eg, atropine) but with a much longer duration of action.

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How does the incapacitating agent 3-quinuclidinyl benzilate affect the human body?

Competes with ACh at the nerve receptors and results in under stimulatin of the receptors.


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3-Quinuclidinyl benzilate (BZ) is a powerful anticholinergic drug that acts on the central nervous system, causing symptoms such as confusion, hallucinations, agitation, and delirium. It blocks the neurotransmitter acetylcholine, leading to a range of effects on the body, including decreased cognitive function, dry mouth, dilated pupils, and increased heart rate. In high doses, BZ can induce incapacitation and potentially be lethal.


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