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Short-term use of Metoprolol does not have an effect on the rate of alcohol elimination; the additive effects of two CNS depressants could cause drowsiness that might make you feel more intoxicated. Long-term use of Metoprolol, however, does cause BAC to increase faster and decrease slower. The abstract below recommends avoiding Metoprolol in combination with high doses of alcohol.

http://www.ncbi.nlm.nih.gov/pubmed/6479058

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