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Acute alcohol intoxication is result of widespread changes in brain metabolism. The greater the amount of alcohol the greater the affect on your brain. One of the mechanisms by which alcohol lowers brain metabolism is via its interaction with GABA receptors. GABA receptors are an inhibitory class of receptors whose function is to reduce the activity of neurons. Many drugs used in the treatment of anxiety also work by this mechanism. Because GABA receptors are ubiquitously expressed, this explains the variety of behavioral changes ensue during inebriation; such as decreased attention span (frontal cortex), slurred speech (motor cortex/cerebellum), social disinhibition and sensations of wellbeing (limbic areas), blurry vision (vestibular-ocular reflex deficits), and poor balance control (vestibular function).

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14y ago

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