Smooth ER of hepatocytes (liver cells) is the site of the cytochrome p450 family of proteins. The CYP450 containing systems are responsible for phase I drug metabolism. Phase I drug metabolism is quite complex and is usually covered in university pharmacology courses. However simply put it can lead to the activation or deactivation of hydrophobic drugs and toxins.
The organelle you are referring to is the smooth endoplasmic reticulum (SER). It plays a key role in detoxifying harmful substances like drugs and alcohol through enzymes, as well as in synthesizing lipids and proteins. The smooth ER lacks ribosomes on its surface, unlike the rough endoplasmic reticulum, which is involved in protein synthesis.
Rough ER (endoplasmic reticulum) manufactures membranes and secretory proteins. In pancreatic cells, the rough ER produces insulin. (has ribosomes attached to it) Smooth ER is responsible carbohydrate and lipid synthesis. It serves as a transitional area for vesicles that transport ER products to various destinations. In liver cells the smooth ER produces enzymes that help to detoxify certain compounds. (has no ribosomes) Both help create Ribosomes
It is the Smooth Endoplasmic Reticulum. The Smooth ER is the "hallways" of the cell, that lead products to the Golgi appratus. It synthesis lipids, metabolizes carbohydrates, and detoxifies drugs and poisons. It also stores calcium ions, which are necessary for muscle movement.
The two types of ER are rough ER (endoplasmic reticulum) and smooth ER. Rough ER has ribosomes attached to its surface, where protein synthesis occurs. Smooth ER is involved in lipid metabolism, detoxification of drugs, and storage of calcium ions.
The smooth endoplasmic reticulum (smooth ER) synthesizes lipids, including phospholipids and cholesterol. It also is involved in detoxification processes by metabolizing drugs and other toxins in the liver. Additionally, the smooth ER stores calcium ions that are important for muscle contraction.
Smooth er
Smooth ER produces steroids and lipids. Smooth ER does not require ribosomes. The enzymes help break down drugs and toxins.
Synthetics do not appear in the results of a drugs test.
Smooth ER
Smooth ER it detoxifies poisons, alcohol, and drugs
This should answer your question: Enzymes of the smooth ER help detoxify drugs and poisons, especially in liver cells. Detoxification usually involves adding hydroxyl groups to drugs, making them more soluble and easier to flush from the body. The sedative phenobarbital and other barbiturates are examples of drugs metabolized in the manner by smooth ER in liver cells. In fact, barbiturates, alcohol, and many other drugs induce the proliferation of the smooth ER and its associated detoxification enzymes. This, in turn, increases tolerance to the drugs, meaning that higher doses are required to achieve a particular affect, such as sedation. Also, because some other the detoxification enzymes have relatively broad action, the proliferation of the smooth ER in response to one drug can increase tolerance to other drugs as well. Barbiturate abuse, for example, may decrease the effectiveness of certain antibiotics and other useful drugs.
The organelle you are referring to is the smooth endoplasmic reticulum (SER). It plays a key role in detoxifying harmful substances like drugs and alcohol through enzymes, as well as in synthesizing lipids and proteins. The smooth ER lacks ribosomes on its surface, unlike the rough endoplasmic reticulum, which is involved in protein synthesis.
Rough ER (endoplasmic reticulum) manufactures membranes and secretory proteins. In pancreatic cells, the rough ER produces insulin. (has ribosomes attached to it) Smooth ER is responsible carbohydrate and lipid synthesis. It serves as a transitional area for vesicles that transport ER products to various destinations. In liver cells the smooth ER produces enzymes that help to detoxify certain compounds. (has no ribosomes) Both help create Ribosomes
It is the Smooth Endoplasmic Reticulum. The Smooth ER is the "hallways" of the cell, that lead products to the Golgi appratus. It synthesis lipids, metabolizes carbohydrates, and detoxifies drugs and poisons. It also stores calcium ions, which are necessary for muscle movement.
Smooth ER makes lipids and breaks down drugs and alcohol. hope this helps. :-)
The endoplasmic reticulum (ER) is the cellular organelle responsible for synthesizing cholesterol and aiding in detoxifying poisons through processes like oxidation and conjugation. The smooth ER, a subtype of the ER, is particularly important for these functions due to its lack of ribosomes and focus on lipid metabolism and detoxification.
Smooth ER lacks ribosomes, which are protein-producing organelles. Instead, they detoxify harmful substances and turn them into harmless substances, and they are involved in the production of hormones and lipids.