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The immune system attacks the foreign antigen as if it were any bacterial infection. The B-cell lymphocytes mark the TB with antibodies that helps it remember the bacteria in the future. The macrophage then consumes the TB bacteria and keeps it latent, and the TB is unable to infect the body or be contagious. However, if the immune system fails to contain the TB, or it becomes weakened by age, malnutrition or another disease like AIDS, the TB bacteria can escape and infect the body, which is why people can get TB during old age or without a TB infected person coming in contact with them.

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