How does the possible impact of a chromosomal mutation that occurs during meiosis differ from that of a similar event that occurs during mitosis of a body cell not involved in reproduction?

Answer 1

If the mutation occurs during meiosis, the mutation will be incorporated into a gamete. If that gamete is the one that eventually fuses with another gamete (i.e. if it's the sperm that fertilizes the egg), that mutation will be passed on to the offspring. As all the offspring's cells are the result of the first two gametes, all the organism's cells will have that mutation. Obviously this can have dire consequences for the offspring, if the mutation is harmful.

If instead it occurs during mitosis, it won't get inherited by the offspring, so any harmful effects are limited to you. Basically it's like getting a wound, you may heal or not, but you won't pass that wound on to any offspring you may subsequently have.

Answer 2

A chromosomal mutation during meiosis can result in genetic variability in offspring due to the formation of gametes with altered chromosomes. In contrast, a similar mutation during mitosis of a body cell not involved in reproduction can lead to a mosaic pattern of affected and unaffected cells in the individual's body. This can result in a localized impact on tissues or organs depending on the extent of mosaicism.

Answer 3

The effects of a mutation occuring in meiosis will be seen in the individual's offsring. The effects of a mutation occuring in mitosis will only be seen in the individual.